New Windows 10 computers with high-DPI screens will exhibit a Remote Desktop screen with tiny icons which are sometimes too small to see.  This can be resolved by using “manifest” files.  Here’s how:

1. Navigate to HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\SideBySide

2. Right click on the SideBySide folder and then click on New, DWORD (32Bit)

3. Create a new key called PreferExternalManifest and set its value to 1.

4. Close Registry Editor

5. Download and un-zip this pre-configured manifest file and place the mstsc.exe.manifest file in the same folder as the MSTSC.EXE file (C:\Windows\System32)

Scaling should be readable now.