UPDATE: The problem described below seems to have been limited to Outlook using Exchange accounts located on Microsoft’s Hosted Exchange service. Later in the day, the problem resolved itself probably after Microsoft corrected a bug in their Exchange Server. So we stopped performing this fix on client machines pending any further trouble reports. We’ll leave the earlier description & fix below in case it comes up again.

We received multiple reports of Outlook crashing immediately after opening following the installation of a botched Office update from Microsoft. Resolves by rolling back. In command window:

cd “\Program Files\Common Files\microsoft shared\ClickToRun”

officec2rclient.exe /update user updatetoversion=16.0.12827.20470

No reboot is required afterward. We have been turning off automatic updating of Office suite after doing this.